1. The "1011 Insider Whale" suffered a paper loss of over $50 million, reducing its total profit to $50.47 million; 2. The "Big Brother Machi" account has been liquidated 200 times since October 11, resulting in a loss of over $22.88 million; 3. a16z transferred 276,000 COMP tokens to Coinbase Prime; 4. Grayscale: Quantum computing is unlikely to impact cryptocurrency prices by 2026; 5. Federal Reserve Governor Milan: He may remain in office after his term expires at the end of January until a successor is confirmed; 6. CIRCLE acquired Interop Labs, including the Axelar development team; 7. Nasdaq plans to extend trading hours for stocks and trading products to 23 hours; 8. MetaMask launched Bitcoin support, continuing to expand its multi-chain business; 9. The whale "pension-usdt.eth" achieved 11 consecutive winning trades in the past 7 days, with total profits exceeding $25 million; 10. Fed's Williams: Slowing employment and easing inflation risks support Fed rate cuts.